It will also depend on the type of seals you have bought as replacements?
Are they floppy,fairly stiff,or real originals?
Sometimes you will need to loosen the glass/winder frame fixings to allow that to move enough to slide the new ones in,which means removing the handles and door cards.
If they are the naff floppy as a bit of string ones,then you will have to either bond a length of metal "s/s" to stiffen them and cut fixing holes using the originals as patterns or chuck them in the bin.